Education & Training
- MD University of Alicante Medical School, Alicante, Spain
- PhD University of Alicante, Institute of Neuroscience, Alicante, Spain
Gómez-Nieto R. and Rubio M.E. (2009) A bushy cell network in the rat ventral cochlear nucleus. Journal of Comparative Neurology 516:241-263. PMCID: PMC2841288.
Whiting B., Moiseff A. and Rubio M.E. (2009) Cochlear nucleus neurons redistribute synaptic AMPA and glycine receptors in response to monaural conductive hearing loss. Neuroscience 163:1264-1276 PMID: 19646510.
Gómez-Nieto R. and Rubio M.E. (2011) Ultrastructure, synaptic organization, and molecular components of bushy cell networks in the anteroventral cochlear nucleus of the rhesus monkey. Neuroscience. 179:188-207. PMCID: PMC3059371. Cover image. Author (Rubio M.E).
Wang H., Yin G., Rogers K., Miralles C., De Blas A.L. and Rubio M.E. (2011) Monaural conductive hearing loss alters the general expression of the GluA3 AMPA and glycine receptor 1 subunits in Bushy and Fusiform cells of the cochlear nucleus. Neuroscience. 199:438-451 PMCID: PMC3237936.
Rubio M.E., Fukazawa Y., Kamasawa N., Clarkson C., Molnár E. and Shigemoto R. (2014) Target- and input-dependent organization of AMPA and NMDA receptors in synaptic connections of the cochlear nucleus. J Comp Neurol. 522:4023-4042. doi: 10.1002/cne.23654. Epub 2014 Jul 29. PMID: 25041792.
Rubio M.E. and Nagy J.J. (2015) Connexin36 expression in major centers of the auditory system in the CNS of mouse and rat: Evidence for neurons forming purely electrical synapses and morphologically mixed synapses. Neuroscience 2015 Jul 15;303:604-629. doi: 10.1016/j.neuroscience.2015.07.026. [Epub ahead of print]. 303:604- 629. PMID: 26188286.
Research Interest Summary
Conductive hearing loss impacts social integration- people who are affected by it often become socially isolated. In contrast to complete deafness, the effects of partial hearing loss on the auditory brain are poorly understood. Since hearing impairment is much more prevalent in humans than complete deafness, there is an urgent need to investigate the cellular changes that occur in the central auditory pathway of the hearing impaired. Research in Dr. Rubio's laboratory focuses on elucidating the molecular, anatomical electrophysiological and behavioral changes in central auditory structures in response to conductive hearing loss.
Anatomical and functional properties of auditory nerve synapses, 1/3/2013 – 28/2/2018, NIH/NIDCD, R01 DC013048 (PI)
JEOL Freeze Fracture (JFDII) System, 1/3/2014 - present, NIH, S10 Shared Instrumentation Grant Program (co-PI)