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Carey D. Balaban
Professor, Departments of Otolaryngology, Neurobiology, Communication Science & Disorders, and Bioengineering
University of Pittsburgh
PhD
Eye and Ear Institute, Suite 107
200 Lothrop Street
Pittsburgh, PA 15213
Phone: 412 647-2298
Email: cbalaban@upmc.edu
Fax: 412-647-0108
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| Research Interests |
The primary goal of Dr. Balaban's research has been to develop a rational basis for understanding the neurobiology of the vestibular system so that new therapies for vestibular disorders can be designed. This goal is approached by:
1. Identifying the organization of central vestibular circuits that mediate autonomic and somatic motor responses to vestibular stimulation
2. Identifying neurotransmitters and intracellular signal transduction proteins that are important in these brain circuits
3. Examining the role of these biochemical constituents in responses to challenges from toxins and mechanical (blast) injury
4. Identifying contributions of these mechanisms to the clinical linkage among balance disorders, anxiety disorders (panic with agoraphobia) and migrainous vertigo |
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| Publications |
Koo JW, Balaban CD: Serotonin-induced plasma extravasation in the murine inner ear: possible mechanism of migraine-associated inner ear dysfunction. Cephalalgia 26(11):1310-1319, 2006.
Halberstadt AL, Balaban CD: Selective anterograde tracing of the individual serotonergic and nonserotonergic components of the dorsal raphe nucleus projection to the vestibular nuclei. Neuroscience 147(1):207-23, June 2007.
Guthrie OW, Li-Korotky HS, Durrant JD, Balaban CD: Cisplatin induces cytoplasmic to nuclear translocation of nucleotide excision repair factors among spiral ganglion neurons. 2008 May;239(1-2):79-91. Epub 2008 Feb 8.
Ying, Y-L M, Balaban CD. Regional distribution of manganese superoxide dismutase 2 (Mn SOD2) expression in rodent and primate spiral ganglion cells. Hearing Research. 2009, 253, 116-124.
McBurney DH, Balaban CD A heuristic model of sensory adaptation. Attention, Perception and Psychophysics, in press
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| Education |
University of Chicago
PhD - Anatomy
Chicago, Illinois |
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| Grants |
RO1 - DC00739-18A1
Vestibulo-Cerebellar Circuits
3/1/09-2/28/14
PI 45%
NIH
5RO1DC003732-11
Vestibular Regulation of Respiratory Muscle Activity
12/1/08-11/30/09
Co-Investigator 5%
NIH |
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